tolerance

[skagardener]

well i was just wondering what others opinions where on this. when i started doing salvia i tried 10x first, then moved to 20x, then i tried the 10x again and found it did just as good. im not sure if this is because i know what to look for and how to set my environment better now, or if there is a reverse tolerance to salvia, i have now gotten to the point where plain leaf off my plant is doing the job, with a pinch of 10x in the mix. also when i first started doing salvia i wanted to do it everyday, or as much as possible, the more i have done it the less i want to, and i have found myself trying to make myself do it. now i usually only do it about every 2-3weeks, but at one point i was only doing it about once or twice every 2 months. anyone else have a take on this or a personal report?

[MstryShovel]

your not alone in this beleive me. many people have talked about reverse tolerance with SD, hypothesizing it like with weed, where once its in your system your body knows whats going on so its like oh yeah heres this thing BOO YAH.  Theres things out there that talk about (in terms of addiction/desire to do it repeatedly) that speak on the receptor in your brain that eats Salvatorin A  is one of the receptors that is incredibly NON habit forming. an example being Opium (which SD is SIMMILAR but not really close) effects 2 "opioid receptors" one of which is extremely habit forming and the other non. the non habit forming one is the same as SD and opium only slightly triggers this one, which leads to the halucinations. but it vigorusly triggers the habit forming one giving the euphoria and general body high type thing that.  Anyways SD affects the receptor that actualy deters habit forming activity, mostly I think cause its no real "good feeling" or rather ill call it "safe feeling" that you get from other drugs where your body calms and you get a slight happyness (ex. weed)

Any time Ive done SD i would be less inclined to call it pleasurable, so much as intense. thats not to say I dont enjoy it, but its not a happy mushroom or acid trip. Its one of those things that I would call a "harsh introspective nightmare."  If I didnt have recurring and intense night terrors all my life (and i mean bad) I dont think i could handle a SD spiral quite so well. I would at least freak out alot more later. Thats also not to say i dont get enjoyable feelings out of my tripps. but i would be more inclined to describe them as intense rather than enjoyable. I reckon this is what detriments most people from taking it on a constant basis, like an acid trip, unless your a crazy MFer you dont nessesarily want to take it every day because its so intense and draining emotionaly (thats also not to say i havent done that aswell).

anyways my 2c

[Paradoxic]

Yeah it definitely does seem to have a reverse-tolerance effect. I only need plain leaves to trip now.

And yeah life Mystry said there is evidence that k-opioid receptor antagonists moderate addictive behavior associated with drugs like heroin, meth, cocaine, nicotine, etc. At the moment there is lots of research going on with this and I expect new drugs to come out soon that are derived from salvinorin A.

[skagardener]

too bad anxious lawmakers are pushing illegalization, there would be no chance for that medicine if it were to be illegal

[Paradoxic]

too bad anxious lawmakers are pushing illegalization, there would be no chance for that medicine if it were to be illegal

Actually I think these days even a Schedule I ban wouldn't stop research. This country is becoming more and more tolerant of these substances for their medicinal uses. Take a look at this, psilocybin is being tested for cancer patients: http://www.canceranxietystudy.org
I also know of someone doing research with synthetic psilocybin, which is a schedule I substance.

However, in many ways a ban would inhibit research. It would probably mostly affect research dealing with the plant itself; the kind of research where you have to actually grow live plants.

[skagardener]

i had seen and read about one particular clinical trial. it had alot to do with religion. i cant seem to find the article right now. and it seemed that everyone had raised as much hell as possible over it, the ignorance scares me...

[Arcygenical]

My standardized dose, to get the same effects as most of you, is 32.1mg of pure salvinorin A... That's about 16 grams of regular leaf, or 2 grams of 10x leaf.

I'm a HUGE hardhead, unfortunately.

[skagardener]

thats wild, i got out of body with just a bowl of 10x, that is in the right environment, i have done a bowl and a half of 20x in the same environment and it was just too much.

[Arcygenical]

thats wild, i got out of body with just a bowl of 10x, that is in the right environment, i have done a bowl and a half of 20x in the same environment and it was just too much.

Yep... I know, it's really sad. I think I'll be experimenting with standardized blotter paper or by impregnating flavored wax.

[skagardener]

i have wanted to do that for a while, i figured i would just soak blotter in tincture

[Arcygenical]

i have wanted to do that for a while, i figured i would just soak blotter in tincture

The best way would be to dissolve the required dosage in a milliliter of acetone...  Deposit the acetone on the blotter paper, then add the salvinorin A powder, swirl it around with a pinhead and let it dry...

[MstryShovel]

THIS sounds intresting! doing the blotter paper! arrg!

[jmtx]

lol just reading the forums and came across this, using blotter paper, if that becomes a trend the media will jump all over it, ive seen 3 reports from fox news saying how salvia is very similar to lsd, and if we start usin sd like this idk but im sure the media would jump on it. still a very saweet idea!

[Arcygenical]

One of my best friends had a wicked idea... I think it's brilliant actually.

Go out and get some hard candies (mints preferred) and place them in the freezer.

Dissolve up to 5mg of Salvinorin A into a drop of acetone, and drop it onto the cold mint.

Let it evaporate, and... You've got an awesome way to take it sub lingually.

I must try this.

[skagardener]

  i like the idea, if you try it and it works pretty well, definitely let me know so i can