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Transdermal application of salvinorin.
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Topic: Transdermal application of salvinorin. (Read 614 times)
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JD1stTimer
Hardhead
Expertise 18
Posts: 533
Transdermal application of salvinorin.
«
on:
February 08, 2008, 02:36:10 am »
Salvinorin-a is a terpenoid, and from what I've read on terpenoids they can cross through the skin. Has anyone tried using a poultice of salvia divinorum to see if you could get long-lasting effects without having a bitter quid and a bucket of saliva in your mouth? I think the skin area covered by the poultice would determine the intensity, and the potency of the poultice would determine the length of effects. Any ideas/experience on this? If no one has tried it I would like to once I can harvest enough leaves. Mentholatum may help to increase bloodflow to the skin surface. Make a paste of Vicks and ground salvia, apply to a bandage, and tape it to the thin skin of the chest? Maybe even use an exfoliant on the area first.
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Salvia goatse'd me! Warn your children! It's actually a good reason to keep it legal, your friendly neighborhood drug pusher doesn't do age verification.
SynapticFlatulence
Apprentice
Expertise 4
Posts: 142
Re: Transdermal application of salvinorin.
«
Reply #1 on:
February 08, 2008, 09:12:53 am »
sally d's all natural cosmic deodorant
Now with 25% more Salvinorin A !!!
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Arcygenical
Cultivation Contributor
Shaman
Expertise 89
Posts: 1105
Re: Transdermal application of salvinorin.
«
Reply #2 on:
February 08, 2008, 05:38:38 pm »
I doubt that using a pure leaf, ground or otherwise, would be a good vector for trying dermal absorption. I would take an extract, measure it out properly, and add the chemical into the adhesive on a bandage. I would be afraid of a chemical in Vicks that might lock out Salvinorin A, or destroy it.
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JD1stTimer
Hardhead
Expertise 18
Posts: 533
Re: Transdermal application of salvinorin.
«
Reply #3 on:
February 08, 2008, 08:56:45 pm »
Hmm... I guess that could be a problem... Oh well, if I ever have a huge amount of leaves that I can spare for it I might just try anyway. Of course, that would be a long ways away, since my Sally is still little more than a stick.
You just never know what could work until you try!
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Salvia goatse'd me! Warn your children! It's actually a good reason to keep it legal, your friendly neighborhood drug pusher doesn't do age verification.
Paradoxic
The Creator
Administrator
Shaman
Expertise 67
Posts: 1127
Re: Transdermal application of salvinorin.
«
Reply #4 on:
February 12, 2008, 12:44:02 am »
Quote from: Arcygenical on February 08, 2008, 05:38:38 pm
I doubt that using a pure leaf, ground or otherwise, would be a good vector for trying dermal absorption. I would take an extract, measure it out properly, and add the chemical into the adhesive on a bandage. I would be afraid of a chemical in Vicks that might lock out Salvinorin A, or destroy it.
...or react with it and create an explosion, lol.
Anyway, I do wonder if this would be possible. I remember seeing an eBay listing for Salvia "creme" that you rub into your skin to trip...I thought it was total bs, but maybe not... Although I haven't seen anything like it since.
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Arcygenical
Cultivation Contributor
Shaman
Expertise 89
Posts: 1105
Re: Transdermal application of salvinorin.
«
Reply #5 on:
February 12, 2008, 12:45:03 am »
They sell caffeine in soaps, so who knows
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DrYRHead
Moderator
Hardhead
Expertise 27
Posts: 687
Re: Transdermal application of salvinorin.
«
Reply #6 on:
February 12, 2008, 02:31:12 am »
One has gotten 20X SD resin on his hands several times. one rubbed into his skin with cream, and no effects were noted at all. Thus, I'm thinking that Salvinorin A can not work that way.
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JD1stTimer
Hardhead
Expertise 18
Posts: 533
Re: Transdermal application of salvinorin.
«
Reply #7 on:
February 12, 2008, 06:44:55 pm »
Was it accidental or intentional?
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Salvia goatse'd me! Warn your children! It's actually a good reason to keep it legal, your friendly neighborhood drug pusher doesn't do age verification.
Madmax
Apprentice
Expertise 2
Posts: 53
Re: Transdermal application of salvinorin.
«
Reply #8 on:
June 11, 2008, 11:05:54 am »
You'd probably need a vehicle such as DMSO to penetrate the skin, and depending on the strength of the extract you could take too much pretty easily.
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Paradoxic
The Creator
Administrator
Shaman
Expertise 67
Posts: 1127
Re: Transdermal application of salvinorin.
«
Reply #9 on:
June 12, 2008, 02:34:18 am »
Yeah, it seems pretty far-fetched. However, does anyone know of any other drugs that can be absorbed that way...?
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Cheveyo
Apprentice
Expertise 0
Posts: 56
Re: Transdermal application of salvinorin.
«
Reply #10 on:
June 14, 2008, 02:06:24 am »
Quote from: Paradoxic on June 12, 2008, 02:34:18 am
Yeah, it seems pretty far-fetched. However, does anyone know of any other drugs that can be absorbed that way...?
LSD in a headband.
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The longest journey, is the journey within.
plur
Experimenter
Expertise 0
Posts: 21
Re: Transdermal application of salvinorin.
«
Reply #11 on:
June 17, 2008, 01:18:58 am »
Quote from: Cheveyo on June 14, 2008, 02:06:24 am
Quote from: Paradoxic on June 12, 2008, 02:34:18 am
Yeah, it seems pretty far-fetched. However, does anyone know of any other drugs that can be absorbed that way...?
LSD in a headband.
well not quite i heard he would put little cuts on his scalpe for it to enter his blood stream any way he did massive dose of lsd my friends dad used to roudy for him and he siad that he would just puor acid like a beer and drink it
i am talking jugs of acid a night. one time on tour jimi send he out too pick up 3 litters of acid next
it was all gone --well at lest thats what he told the was pretty burnt him self so he was probly did alot him self
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longjourney
Guest
Re: Transdermal application of salvinorin.
«
Reply #12 on:
June 17, 2008, 10:14:28 am »
Quote from: Cheveyo on June 14, 2008, 02:06:24 am
Quote from: Paradoxic on June 12, 2008, 02:34:18 am
Yeah, it seems pretty far-fetched. However, does anyone know of any other drugs that can be absorbed that way...?
LSD in a headband.
The guys in the background are picking straws to see who will tell Jimmy the concert has been over for at least an hour
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Arcygenical
Cultivation Contributor
Shaman
Expertise 89
Posts: 1105
Re: Transdermal application of salvinorin.
«
Reply #13 on:
June 18, 2008, 11:16:38 pm »
Quote from: plur on June 17, 2008, 01:18:58 am
i am talking jugs of acid a night. one time on tour jimi send he out too pick up 3 litters of acid next
it was all gone --well at lest thats what he told the was pretty burnt him self so he was probly did alot him self
Ok, I'm calling shens on that one...
30ml of most water LSD tincture will usually contain between 15000ug and 25000ug of LSD... 3 Liters would contain roughly two million micrograms of LSD, or about 2g of the chemical. At this dosage, humans will, almost definitely, succumb to cardiac arrest or respiratory failure... Hell, a dose of around 1mg/kg (around 1200x the regular dose) is often reported as fatal... Although, I've seen people personally thumbprint 100mg to no ill effects (other than tripping for a good 48 hours).
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Selling 20x Salvia. Cheaper than store bought!
hazyshaman
Apprentice
Expertise 4
Posts: 131
Re: Transdermal application of salvinorin.
«
Reply #14 on:
June 19, 2008, 01:25:38 pm »
Actually believe it or not, rectal tissue has the highest absorption rate of any skin on your body. If you could fill a suppository with salvinorin A pure crystals with a neutral base I'm almost sure it will work. I'm not too keen about having stuff in my anal cavity, but if you were up to it,it could work.
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The day I let the government control my consciousness is the day I give up personal freedom.
"Emancipate yourselves from mental slavery. None but ourselves can free our minds" Bob Marley
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