Time Immemorable- Salvia divinorum likely has a long history of human usage in entheogenic and shamanic ceremonies in Central America, but how far back its history goes is unknown. Robert Gordon Wasson has theorized that Salvia divinorum may be the psychoactive known to the Aztec as "Pipiltzintzintli", if this is true then the human usage of Salvia divinorum is likely 1000s of years old.
1938 A.D.- Jean B. Johnson reports learning of a Mazatec tea made from the beaten leaves of a "hierba Maria", and used for divination. This is the oldest verifiable recorded use of Salvia divinorum known, while many theories and speculations exist, the human usage Salvia divinorum has never been
proven to be more than 100 years old.
1945 A.D.- Blas Pablo Reko reports a "magic plant" called “hoja de adivinación” (leaf of prophecy), used by Cuicatecs and Mazatecs to produce visions. It was probably Salvia divinorum.
1952 A.D.- Roberto Weitlaner reports a "yerba de María" in Oaxaca. It is said to be used by curanderos.
1957 A.D. - Mexican botanist A. Gómez Pompa collects specimens of a hallucinogenic Salvia plant he describes as "Xka Pastora". His specimens cannot be identified at the species level.
1960 A.D.- R. Gordon Wasson collects samples of S. divinorum, but they are inadequate for botanical identification.
July, 12, 1961 A.D.- Wasson ingests Salvia divinorum, and experiences effects.
June, 1962 A.D.- Sterling Bunnel brings the first live Salvia divinorum plants to the United States from Huautla de Jiménez. Cuttings from this sample are widely-propagated and are commonly available to this day sold erroneously as the "Wasson and Hofmann" strain.
October, 9, 1962 A.D.- Wasson and Anita Hofmann, wife of Albert Hofmann, ingest juice of Salvia divinorum in a ceremony conducted by curandera Maria Sabina.
December, 1962 A.D.- Wasson and Hofmann collect flowering samples for identification. Carl Epling and colleagues identify it as a novel species and give it the name "Salvia divinorum".
1963 A.D.- Wasson tentatively proposes Salvia divinorum as a candidate for the unidentified Aztec plant sacrament "pipiltzintzinli". If correct, this widely-contested hypothesis would imply a long history of cultivation and use, yet this remains unconfirmed.
1975 A.D.- Ott and Diaz contemporaneously observe persons smoking dried Salvia divinorum leaves in Mexico City. There is no known report of Salvia divinorum being smoked prior to this time, and it appears to be a novel use of the plant.
1982 A.D.- Ortega et al. publish a paper describing their isolation of a novel compound from Salvin divinorum, which they call Salvinorin.
1984 A.D.- Valdes et al. identify two Salvia divinorum derivatives which they call divinorin A and B. Divinorin A is found to be identical to the Ortega's salvinorin, so the compounds are re-named salvinorin A and B.
1994 A.D.- Siebert sponsors investigation into several possible mechanisms of action for salvinorin A, but finds no evidence that it interacts with any of a few dozen common neurotransmitters and peptides. Several possibilities are eliminated, but its mechanisms of action remain unknown.
Late 1990s A.D.- Salvia becomes available commercially online and its public visibility dramatically increases.
2002 A.D.- Roth et al. report that salvinorin A is a highly-selective kappa-opioid agonist, solving the long time mystery of its site of action.
August, 2005 A.D.- Louisiana becomes the first state in the U.S.A. to ban human consumption of Salvia divinorum, several other states follow.
December, 2009 A.D.- North Carolina passes progressive legislature banning Salvia divinorum for recreational consumption but exempting scientific research and ornamental cultivation from restriction.
Early 2010s A.D.- Many nations world wide have made Salvia divinorum illegal or restricted it in some way including about half the states in the U.S.A. as well as Australia, Belgium, Denmark, Estonia, Finland, Italy, Japan, Spain, Sweden and many other nations.
201? A.D.- What will be the next big thing to happen to Salvia divinorum? HELP ME FINISH THIS TIME-LINE AND HELP KEEP SALVIA DIVINORUM LEGAL!!!